Our research focuses on metabolic regulation of non-conventional T cells and their role for the development of liver diseases.
Chronic liver diseases and their complications affect a large population worldwide and represent a major health burden. They can develop from various stimuli, although inflammation is considered as a key pathogenic driver. Mucosal-associated invariant T (MAIT) cells, innate-like T cells, are particularly enriched in the liver and are important mediators of hepatic inflammation.
Our research group is investigating the regulation of MAIT cell activation and function through metabolic reprogramming and their relevance for the development of non-alcoholic fatty liver disease (NAFLD) and its complications. The group closely collaborates with the Institute of Molecular Immunology and Experimental Oncology, TUM.
MD/PhD thesis | Grant support
Applications for a PhD or MD degree are welcome. Please apply via email.
Deutsche Forschungsgemeinschaft (DFG)
Kommission für Klinische Forschung (KKF)