Klinik und Poliklinik
für Innere Medizin II
Klinik und Poliklinik für Innere Medizin II
Direktor: Univ.-Prof. Dr. med. Roland. M. Schmid
direktion.med2@mri.tum.de

Principal Investigator Dr. med. Dr. rer. nat. Yizhu Li

Our group investigates the translational application of novel DNA modifications and the associated DNA damage response.

Team

Team

  • Dr. med. Dr. rer. nat. Yizhu Li (PI)
  • Olivia Wan Cheng Oh, MSc. (lab manager)
  • Dragan Sandulovic, Bsc. (Msc. cand.)
  • Yurong Ling, Bsc. (Msc. cand.)
  • Sabrina Chaabane, Bsc. (Msc. cand.)
  • Helena Lachermeier, Bsc. (Dr. med. cand., DGVS doctoral scholarship)
  • Marina Munker (Bsc. cand.)
  • Badr Al Khatib (Bsc. cand.)
  • Omar Ismail (Bsc. cand.)
  • Ronja Pientka (Bsc. cand.)

Alumni

  • Sarah Christ, BSc.
  • Tim Schellner, BSc.

Research background

Our research investigates the translational application of novel DNA modifications. We utilize the highly specific click chemistry reactions to modify cellular DNA in the cell culture but also in the living mouse. Depending on the added structure, these have a variety of downstream functions such as in differential cellular toxicity and molecular diagnostics. Additional topics of interest include the physiology of DNA damage and repair in response to various chemotherapeutic agents, and the pharmacological control of the cell cycle to induce selective cellular toxicity.

Publications

Thesis work | Grant support

Thesis work

If you are interested in a Bachelor's/Master's thesis in the field of life science or a medical doctoral thesis, please forward me your application via e-mail (yizhu.li@tum.de).

 

Grant support

  • Kommission für Klinische Forschung (KKF)
  • Else-Kröner-Fresenius-Stiftung (2021-EKEA.117)

Contact

Head: Dr. med. Dr. rer. nat. Yizhu Li
Klinik und Poliklinik für Innere Medizin II
Klinikum rechts der Isar
Technische Universität München
Ismaninger Straße 22
81675 München
Tel: (089) 4140 - 9690

E-Mail: yizhu.li@tum.de