Klinik und Poliklinik
für Innere Medizin II
Klinik und Poliklinik für Innere Medizin II
Direktor: Univ.-Prof. Dr. med. Roland. M. Schmid
direktion.med2@mri.tum.de

Principal Investigator Dr. Stein-Thoeringer

Neuro-psycho-gastroenterology: Principles of visceral nociception and mechanisms of microbiota-gut-brain interactions.

Team

Laboratory members

  • Dr. med. Christoph Stein-Thöringer, PI
  • Danica Bajic, Msc, PhD student
  • Dr. med. Johanna Bobardt
  • Rebeca Cruz Aguilar, PhD student
  • Julia Eberl, MD student


Former members

(contact details via Christoph Stein-Thöringer)

  • Eva Auffenberg
  • Marcel Hess, MD student
  • Angela Jurik

Research background

Research areas in Neuro-Psycho-Gastroenterology – Basic research on visceral pain

Visceral pain represents of the core symptoms of functional gastrointestinal disorders. Our research group is working on the development, refinement and validation of animal models of visceral nociception with a special focus on behavioral phenotyping.

Current hypotheses propose strong analogies of the development and maintenance of pain to processes underlying learning and memory. Special interest is thus set on the neurobiology of nociception to elucidate the biological signature of pain in spinal and cerebral neuronal networks.

 

Pain and emotion in intestinal inflammation und tumor

Patients suffering from inflammatory bowel disease or gastrointestinal malignancies frequently present chronic pain syndromes and psychiatric comorbidities such as depressive episodes or anxiety disorders. Another research area focuses on the pathophysiology of visceral nociception and alterations of emotionality in clinically relevant animal models of intestinal inflammation and tumors. A detailed characterization of phenotypes is proposed a superior basis for further in depth – analyses of neurobiological, endocrine and genetic mechanisms underlying these syndromes. Using a translational approach, we are finally working on novel psychopharmacological and analgetic therapy strategies to treat visceral pain and affective disturbances in these diseases.

 

Publications ⎮ Medical theses ⎮ PhD

Publications

PubMed



Medical theses/PhD

If you are interested in performing experiments and writing a master or doctoral thesis in a vibrant scientific atmosphere please contact Dr. Stein-Thöringer (cf. contact).

 


Contact

Head: Dr. Christoph K. Stein-Thöringer
Klinik und Poliklinik für Innere Medizin II
Klinikum rechts der Isar der TUM
Ismaninger Str. 22
81675 Munich, Germany

Tel.: (0 89) 41 40 - 41 26 (lab) / - 69 16 (office)
Fax: (0 89) 30 62 - 26 10
Email: christoph.thoeringer@tum.de

Lab at the
Institut für Mikrobiologie
Trogerstraße 30
81675 Munich, Germany